- ALLEGED FATHER
A man who is contesting an accusation of paternity or wishes to establish it when a question
of paternity exists
- ALLELE
Alternate forms of the same gene. Same as a genetic marker. Examples are: A, B and +O of the ABO
blood gene
- AMNIOCENTESIS
The surgical withdrawal of a sample of amniotic fluid from a pregnant female for the use in the
determination of sex or genetic disorder in the fetus
- ANTIGEN
A substance that when introduced into the body stimulates the production of an antibody
- BUCCAL SWAB
Specimen of the cavity of the mouth removed with a swab
- CHROMOSOME
Structures in cells which contain genes. There are 46 chromosomes in humans, one-half of
which are contributed to the child by each biological parent
- CYTOGENETIC STUDIES
The study of heredity by cytological and genetic methods
- CYTOLOGY
The branch of biology dealing with the study of the formation, structure, and function of cells
- DNA (DEOXYRIBONUCLEIC ACID)
A compound which regulates all genetic systems. DNA is itself a genetic
factor that can be tested in forensic and parentage disputes
- ELECTROPHORESIS
A technique used to evaluate genetic components based on their migration in an electric
field. The technique separates alleles into different regions so they can be differentiated. Electrophoresis is commonly used to evaluate red cell enzymes, serum proteins and DNA
- GENE
A specific hereditary trait, such as blood type, eye color, etc. Gene also refers to a specific DNA region. Many genes have alternate forms referred to as alleles
- HLA (HUMAN LEUKOCYTE ANTIGEN)
Genetic markers found on the surface of leukocytes
- LEUKOCYTE
Any of the white or colorless nucleated cells occurring in blood
- PCR (POLYMERASE CHAIN REACTION)
Method of DNA analysis that amplifies a specific DNA (gene) region
allowing rapid DNA analysis
- PHLEBOTOMY
The therapeutic practice of opening a vein to draw blood
- POLYMORPHISM
Variable number of alleles for a test system. Systems that are highly polymorphic provide a
greater power of exclusion
- PROBE
A DNA strand that is used to stain DNA fragments after electrophoresis
- RED BLOOD CELL
An erythrocyte (the yellowish, nonnucleated, disk-shaped blood cell that contains hemoglobin
and is responsible for the color of blood)
- RED BLOOD CELL ANTIGENS
Genetic markers found on the surface of red cells
- RESTRICTION FRAGMENT LENGTH POLYMORPHISM (RFLP)
Variations in the size of DNA fragments
produced by a restriction enzyme at a polymorphic locus
- SERUM PROTEINS
Genetic markers found floating in the blood along with red and white cells
- VENIPUNCTURE
Puncture of a vein, as for drawing blood, intravenous feeding, or administration of medicine