This brief, using qualitative data collected during the Hispanic Healthy Marriage Initiative Grantee Implementation Evaluation, describes the adaptations and refinements undertaken by study sites to make their services more culturally responsive to address the backgrounds and life circumstances of people of different cultural, racial, ethnic, or socio-economic backgrounds. The adaptations included addressing issues of language, diversity, racism, and immigration, and incorporating cultural constructs like familismo, confianza, personalismo, and respeto. These adaptations were made to improve the recruitment, retention, overall participation, and effectiveness of the programs. The study was not designed to examine the overall efficacy of these adaptations, but rather to document them. More research is needed to examine whether these adaptations contribute to program outcomes.