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The Office of Planning, Research and Evaluation (OPRE) in the Administration for Children and Families (ACF), U.S. Department of Health and Human Services, held the 14th Annual Welfare Research and Evaluation Conference on June 1—3, 2011 in Washington, DC. The conference centered on the Temporary Assistance for Needy Families (TANF) program, with significant attention also provided to related programs, policies, and services that support low-income and vulnerable families on the path to economic self-sufficiency.